Vaginal misoprostol versus intracervical Foley catheter for cervical ripening in postdate primigravid women: a randomized clinical trial

Abstract Background Being one of the most common indications labor induction, postdate pregnancy can lead to serious maternal and fetal complications. In this study we aimed compare vaginal misoprostol with intracervical Foley catheter (FC) for cervical ripening in primigravid women. Methods This randomized clinical trial included 120 women aged 18–35 years singleton, pregnancies, Bishop score ? 4. Participants were into two equal groups. The first group received 25 µg second had an 18 Fr FC inserted their canal. Labor induction was performed using oxytocin both groups if progression or true contractions did not occur within 6 h interventions. case nonreassuring heart rate, distress, placental abruption, prolonged labor, C-section performed. Results frequency normal delivery, Cesarean section, meconium-stained amniotic fluid, neonatal intensive care unit admission differ significantly between Placental abruption uterine tachysystole occurred more frequently (15.0 vs. 1.7%, P = 0.008 21.7 0.0%, < 0.001, respectively). A higher number required (73.3 41.7%, 0.001). Duration ( Conclusions Due lower rate observed FC, it appears be superior women; however, its longer duration requirement should taken consideration. Trial registration Iranian Registry Clinical Trials, IRCT20181218042033N4 . Registered 19/04/2020. Retrospectively registered, https://www.irct.ir/trial/47037